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A potent CDK inhibitor
Catalog #: 9537
SKU-Size Size Price Qty
9537-5 5 mg
9537-25 25 mg
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Product Details

Alternate Name 2-[(2S)-1-[3-ethyl-7-[(1-oxidopyridin-1-ium-3-yl)methylamino]pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-2-yl]ethanol; SCH-727965
Appearance Light brown solid
CAS # 779353-01-4
Molecular Formula C₂₁H₂₈N₆O₂
Molecular Weight 396.49
Purity ≥98% by HPLC
Solubility DMSO (>20 mg/ml)
InChi InChI=1S/C21H28N6O2/c1-2-17-14-23-27-19(22-13-16-6-5-9-25(29)15-16)12-20(24-21(17)27)26-10-4-3-7-18(26)8-11-28/h5-6,9,12,14-15,18,22,28H,2-4,7-8,10-11,13H2,1H3/t18-/m0/s1
PubChem CID 46926350
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Dinaciclib is a potent and selective cyclin-dependent kinase (CDK) inhibitor displaying selectivity for CDK1, CDK2, CDK5 and CDK9 with IC₅₀ values of 3, 1, 1 and 4 nM respectively. It has been shown to inhibit DNA synthesis by blocking thymidine incorporation in A2780 ovarian cancer cells with an IC₅₀ value of 4 nM.

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