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Digoxin

A P-glycoprotein model substrate
Catalog #: 2911
SKU-Size Size Price Qty
2911-100 100 mg
$65.00
2911-500 500 mg
$125.00
More Sizes Get Quote

Product Details

Alternate Name 12 beta-Hydroxydigitoxin, Lanoxin
Appearance Clear to white crystalline powder
CAS # 20830-75-5
Molecular Formula C₄₁H₆₄O₁₄
Molecular Weight 780.95
Purity ≥96% by HPLC
Solubility Pyridine (50 mg/ml), DMSO (>70 mg/ml)
SMILES CC1C(C(CC(O1)OC2C(OC(CC2O)OC3C(OC(CC3O)OC4CCC5(C(C4)CCC6C5CC(C7(C6(CCC7C8=CC(=O)OC8)O)C)O)C)C)C)O)O
InChi InChI=1S/C41H64O14/c1-19-36(47)28(42)15-34(50-19)54-38-21(3)52-35(17-30(38)44)55-37-20(2)51-33(16-29(37)43)53-24-8-10-39(4)23(13-24)6-7-26-27(39)14-31(45)40(5)25(9-11-41(26,40)48)22-12-32(46)49-18-22/h12,19-21,23-31,33-38,42-45,47-48H,6-11,13-18H2,1-5H3/t19-,20-,21-,23-,24+,25-,26-,27+,28+,29+,30+,31-,33+,34+,35+,36-,37-,38-,39+,40+,41+/m1/s1
InChi Key LTMHDMANZUZIPE-PUGKRICDSA-N
PubChem CID 87568294
MDL Number MFCD00003674
Handling Protect from light and moisture
Storage Conditions RT
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Digoxin is a cardiac glycoside from the leaves of Digitalis lanata. It is used to treat cardiac arrhythmias. It is often used as a model substrate of P-glycoprotein (0.01-10 µM) and an inhibitor of Na+/K+-ATPase.


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