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Digitoxin

A lipid soluble cardiac glycoside
Catalog #: B2578
SKU-Size Size Price Qty
B2578-10 10 mg
$75.00
B2578-50 50 mg
$265.00
More Sizes Get Quote

Product Details

Alternate Name 3-[(3S,5R,8R,9S,10S,13R,14S,17R)-3-[(2R,4S,5S,6R)-5-[(2S,4S,5S,6R)-5-[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl] oxy-4-hydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-14-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15, 16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one, Digitoxoside, Unidigin
Peptide Sequence N/A
Appearance White to off-white solid
CAS # 71-63-6
Molecular Formula C₄₁H₆₄O₁₃
Molecular Weight 764.95
Purity ≥97%
Solubility ~15 mg/ml in Ethanol
SMILES CC1C(C(CC(O1)OC2C(OC(CC2O)OC3C(OC(CC3O)OC4CCC5(C(C4)CCC6C5CCC7(C6 (CCC7C8=CC(=O)OC8)O)C)C)C)C)O)O
InChi InChI=1S/C41H64O13/c1-20-36(46)29(42)16-34(49-20)53-38-22(3)51-35(18-31(38)44)54-37-21(2)50-33(17-30(37) 43)52-25-8-11-39(4)24(15-25)6-7-28-27(39)9-12-40(5)26(10-13-41(28,40)47)23-14-32(45)48-19-23/h14,20-22,24 -31,33-38,42-44,46-47H,6-13,15-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27+,28-,29+,30+,31+,33+,34+,35+,36-,37 -,38-,39+,40-,41+/m1/s1
InChi Key WDJUZGPOPHTGOT-XUDUSOBPSA-N
PubChem CID 441207
MDL Number MFCD00003686
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Digitoxin is a lipid soluble cardiac glycoside that acts as an inhibitor of plasma membrane Na+/K+-ATPase (EC₅₀ = 0.78 µM). Digitoxin shows a significantly cytotoxic effect in H1975 cells by causing G2 phase arrest.


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