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Dichlorphenamide

A potent carbonic anhydrase inhibitor

WARNING: This product can expose you to chemicals including Dichlorphenamide, which is known to the State of California to cause Reproductive toxicity. For more information go to www.P65Warnings.ca.gov.
Catalog #: B3272
SKU-Size Size Price Qty
B3272-10 10 mg
$85.00
B3272-50 50 mg
$335.00
More Sizes Get Quote

Product Details

Alternate Name Diclofenamide 4,5-dichloro-1,3-benzenedisulfonamide
Appearance Solid
CAS # 120-97-8
Molecular Formula C₆H₆Cl₂N₂O₄S₂
Molecular Weight 305.16
Purity ≥98%
Solubility >50 mg/ml DMSO
SMILES C1=C(C=C(C(=C1S(=O)(=O)N)Cl)Cl)S(=O)(=O)N
InChi InChI=1S/C6H6Cl2N2O4S2/c7-4-1-3(15(9,11)12)2-5(6(4)8)16(10,13)14/h1-2H,(H2,9,11,12)(H2,10,13,14)
InChi Key GJQPMPFPNINLKP-UHFFFAOYSA-N
PubChem CID 3038
MDL Number MFCD00148948
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Dichlorphenamide is a potent, orally bioavailable carbonic anhydrase (CA) inhibitor (Kis = 1.20, 38, 50, and 50 nM for the human CA isoforms CAI, CAII, CAIX, and CAXII, respectively). It lowers intraocular pressure in rabbits when 50 µl of a 10% solution is applied topically to the eye. Used in the treatment of glaucoma and primary periodic paralysis.


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