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DG051

A novel small-molecule inhibitor of leukotriene A4 hydrolase (LTA4H)
Catalog #: B1105
SKU-Size Size Price Qty
B1105-1 1 mg
$125.00
B1105-5 5 mg
$495.00
More Sizes Get Quote

Product Details

Alternate Name 4-((S)-2-((4-(4-chlorophenoxy)phenoxy)Methyl)pyrrolidin-1-yl)butanoic acid
Appearance Crystalline solid
CAS # 929916-05-2
Molecular Formula C₂₁H₂₄ClNO₄
Molecular Weight 389.14
Purity ≥98% by HPLC
Solubility DMSO
SMILES C1CC(N(C1)CCCC(=O)O)COC2=CC=C(C=C2)OC3=CC=C(C=C3)Cl
InChi 1S/C21H24ClNO4/c22-16-5-7-19(8-6-16)27-20-11-9-18(10-12-20)26-15-17-3-1-13-23(17)14-2-4-21(24)25/h5-12,17H,1-4,13-15H2,(H,24,25)/t17-/m0/s1
InChi Key PVCTYSQBVIGZRU-KRWDZBQOSA-N
PubChem CID 44537807
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

DG051 is a novel small-molecule inhibitor of leukotriene A4 hydrolase (LTA4H), the protein made by one of the genes in the leukotriene pathway that has been shown to link to risk of heart attack, myocardial infarction and stroke. DG051 is designed to decrease risk of heart attack by decreasing the production of leukotriene B4 (LTB4), an end product of the leukotriene pathway and a potent promoter of inflammation.


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