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Destruxin A

A cyclic hexa-depsipeptide with insecticidal, anti-viral, and phytotoxic properties
Catalog #: B2947
SKU-Size Size Price Qty
B2947-500 500 μg
B2947-1000 1000 μg
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Product Details

Alternate Name 3-(butan-2-yl)-5,8,9-trimethyl-6-(propan-2-yl)-16-(prop-2-en-1-yl)dodecahydropyrrolo[1,2-d][1,4,7,10,13,16]oxapentaazacyclononadecine-1,4,7,10,14,17(11h,16h)-hexone; (3S,6S,9S,16R,21aS)-16-Allyl-3-[(2S)-2-butanyl]-6-isopropyl-5,8,9-trimethyldodecahydropyrrolo[1,2-d][1,4,7,10,13,16]oxapentaazacyclononadecine-1,4,7,10,14,17(11H,16H)-hexone; NSC361126
Appearance Solid
CAS # 6686-70-0
Molecular Formula C₂₉H₄₇N₅O₇
Molecular Weight 577.71
Purity ≥96%
Solubility 10 mg/ml in DMSO
InChi InChI=1S/C29H47N5O7/c1-9-12-21-27(38)34-16-11-13-20(34)26(37)31-23(18(5)10-2)28(39)33(8)24(17(3)4)29(40)32(7)19(6)25(36)30-15-14-22(35)41-21/h9,17-21,23-24H,1,10-16H2,2-8H3,(H,30,36)(H,31,37)
PubChem CID 122810
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Destruxin A is a cyclic hexadepsipeptide metabolite from the fungus Metarhizium anisopliae. Destruxins show insecticidal, anti-viral, and phytotoxic properties. Destruxin A suppresses the Drosophila humoral immune response in Drosophila melanogaster. It increases peptidoglycan recognition protein (PGRP), prophenoloxidase (proPO) system and affects diverse pathways, including apoptosis, calcium signaling, and development in the larvae of Plutella xylostella.

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