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A ERK1/2 inhibitor
Catalog #: B1683
SKU-Size Size Price Qty
B1683-5 5 mg
B1683-25 25 mg
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Product Details

Alternate Name FR180204; FR-180204; FR 180204; 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-2H-pyrazolo[3,4-c]pyridazin-3-amine
Appearance Solid
CAS # 865362-74-9
Molecular Formula C₁₈H₁₃N₇
Molecular Weight 327.34
Purity >98%
Solubility DMSO
InChi InChI=1S/C18H13N7/c19-17-12-10-13(20-22-18(12)23-21-17)15-14-8-4-5-9-25(14)24-16(15)11-6-2-1-3-7-11/h1-10H,(H3,19,21,22,23)
PubChem CID 11493598
MDL Number MFCD14585805
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


FR180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2 with Ki value of 0.31 uM and 0.14 uM respectively; has IC50 values of 0.51 and 0.33 μM in enzymatic assays against ERK1 and ERK2, respectively.

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