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(-)-Deguelin

A naturally occurring flavonoid that displays various biological activities
Catalog #: B2096

In stock

SKU-Size Size Price Qty
B2096-5 5 mg
$115.00
B2096-25 25 mg
$455.00
More Sizes Get Quote

Product Details

Alternate Name (7aS,13aS)-13,13a-Dihydro-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6′,5′-e]pyran-7(7aH)-one
Appearance White to off-white solid
CAS # 522-17-8
Molecular Formula C₂₃H₂₂O₆
Molecular Weight 394.42
Purity ≥98% by HPLC
Solubility DMSO (~10 mg/ml)
SMILES CC1(C=CC2=C(O1)C=CC3=C2OC4COC5=CC(=C(C=C5C4C3=O)OC)OC)C
InChi InChI=1S/C23H22O6/c1-23(2)8-7-12-15(29-23)6-5-13-21(24)20-14-9-17(25-3)18(26-4)10-16(14)27-11-19(20)28-22(12)13/h5-10,19-20H,11H2,1-4H3/t19-,20+/m1/s1
InChi Key ORDAZKGHSNRHTD-UXHICEINSA-N
PubChem CID 107935
MDL Number MFCD01740600
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Deguelin is a naturally occurring flavonoid that displays potent antiproliferative, antimetastatic, and apoptotic activity against several cancers both in vitro and in vivo. deguelin induces cell death by inhibiting several cell signaling pathways, such as PI3K-Akt, IKK-IκBα-NF-κB, AMPK-mTOR-survivin, and HIF-1α-VEGF.


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