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DCXR, human recombinant

Converts xylulose into xylitol
Catalog #: P1155
SKU-Size Size Price Qty
P1155-10 10 μg
$85.00
P1155-50 50 μg
$315.00
More Sizes Get Quote

Product Details

Alternate Name Dicarbonyl/L-xylulose reductase, DCR, HCR2, HCRII, KIDCR, P34H
Gene Symbol DCXR
Gene ID 51181
Source E.coli
Appearance Liquid
Physical Form Description In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 20% glycerol, 50 mM NaCl
Molecular Weight 28 kDa
Purity by SDS-PAGE > 95%
Biological Activity Specific activity is > 1,800 pmol/min/ug
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MELFLAGRRV LVTGAGKGIG RGTVQALHAT GARVVAVSRT QADLDSLVRE CPGIEPVCVD LGDWEATERA LGSVGPVDLL VNNAAVALLQ PFLEVTKEAF DRSFEVNLRA VIQVSQIVAR GLIARGVPGA IVNVSSQCSQ RAVTNHSVYC STKGALDMLT KVMALELGPH KIRVNAVNPT VVMTSMGQAT WSDPHKAKTM LNRIPLGKFA EV
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Dicarbonyl/L-xylulose reductase, also known as DCXR, is an enzyme responsible for the metabolism of xylulose, converting it into xylitol. DCXR was expressed at low levels and was localized predominantly in the cytoplasmic membrane. In contrast, in virtually all grades of early-stage prostate cancer and in all chemohormonally treated cases, DCXR was strikingly overexpressed and was localized predominantly in the cytoplasm and nucleus. Recombinant human DCXR, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.


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