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Dabigatran Etexilate

A reversible and selective, direct thrombin inhibitor (DTI)
Catalog #: B2552
SKU-Size Size Price Qty
B2552-10 10 mg
B2552-50 50 mg
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Product Details

Alternate Name BIBR 953, (E)-ethyl 3-(2-(((4-(N'-((hexyloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate, BIBR953, Pradaxa, BIBR-953
Peptide Sequence N/A
Appearance Crystalline solid
CAS # 211915-06-9
Molecular Formula C₃₄H₄₁N₇O₅
Molecular Weight 627.73
Purity ≥98%
Solubility 0.5 mg/ml in DMSO
InChi InChI=1S/C34H41N7O5/c1-4-6-7-10-21-46-34(44)39-32(35)24-12-15-26(16-13-24)37-23-30-38-27-22-25(14-17-28(27)40(30)3)33(43) 41(20-18-31(42)45-5-2)29-11-8-9-19-36-29/h8-9,11-17,19,22,37H,4-7,10,18,20-21,23H2,1-3H3,(H2,35,39,44)
PubChem CID 6445226
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM. Dabigatran selectively and reversibly inhibits human thrombin (Ki = 4.5 nM) as well as thrombin-induced platelet aggregation (IC50 = 10 nM), while showing no inhibitory effect on other platelet-stimulating agents. Dabigatran displays concentration-dependent anticoagulant effects in various species in vitro.

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