D-Luciferin (Free acid)

A luminescent substrate for firefly luciferase
Catalog #: 2779 | abID:

Product Details

Alternate Name (S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylic acid, 4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-
Appearance White to light yellow solid
CAS # 2591-17-5
Molecular Formula C₁₁H₈N₂O₃S₂
Molecular Weight 280.33
Purity ≥98% by HPLC
Solubility DMSO (~ 10 mg/ml)
InChi InChI=1S/C11H8N2O3S2/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16/h1-3,7,13H,4H2,(H,15,16)/b10-9+/t7-/m1/s1
PubChem CID 5484207
MDL Number MFCD00042929
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Synthetic. StayBrite™ D-Luciferin is a luminescent substrate for firefly luciferase (Km ~2 μM). Note: Unlike the Potassium (Cat. No.7903) or Sodium (Cat. No. 7902) salts, Luciferin free acid is not soluble in water. It requires the addition of dilute NaOH or KOH to aid the free acid to go into solution.

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Joseph L. Jilek, Bioengineered Let-7c Inhibits Orthotopic Hepatocellular Carcinoma and Improves Overall Survival with Minimal Immunogenicity. Mol Ther Nucleic Acids, Jan 2019;  30753993.
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