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D-Fructose 1,6-bisphosphate trisodium salt

An allosteric activator of enzymes such as pyruvate kinase and NAD+-dependent L-(+)-lactate dehydrogenase
Catalog #: B1057
SKU-Size Size Price Qty
B1057-1G 1 g
B1057-5G 5 g
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Product Details

Alternate Name D(+)-Fructofuranose 1,6-diphosphate trisodium salt hydrate, Hexose diphosphate trisodium salt
Appearance White to off-white solid
CAS # 38099-82-0
Molecular Formula C₆H₁₁Na₃O₁₂P₂
Molecular Weight 406.06
Purity ≥98% by assay
Solubility H₂O (50 mg/ml)
SMILES C(C1C(C(C(O1)(COP(=O)(O)[O-])O)O)O)OP(=O)([O-])[O-].[Na+].[Na+].[Na+]
InChi InChI=1S/C6H14O12P2.3Na/c7-4-3(1-16-19(10,11)12)18-6(9,5(4)8)2-17-20(13,14)15;;;/h3-5,7-9H,1-2H2,(H2,10,11,12)(H2,13,14,15);;;/q;3*+1/p-3/t3-,4-,5+,6?;;;/m1.../s1
PubChem CID 70697660
MDL Number MFCD03427650
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


D-Fructose-1,6-bisphosphate (FBP) is an intermediate in the glycolytic pathway, exerting pharmacological actions on inflammation by inhibiting cytokine production or interfering with adenosine production. It may be used as an allosteric activator of enzymes such as pyruvate kinase and NAD+-dependent L-(+)-lactate dehydrogenase, as an inhibitor of acetate kinase and as a substrate to identify and characterize enzymes such as fructose-1,6-bisphosphate aldolase(s) and fructose-1,6-bisphosphatase(s).

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