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Cytochrome c Antibody (Clone 7H8.2C12)

based on 7 citations in multiple journalsCytochrome c Antibody (Clone 7H8.2C12)74.1 4
Catalog #: 3026

Product Details

Cat # +Size 3026-50
Size 50 µg
Antibody Target Cytochrome c
Alternate Name CYCS, CYC
Host Mouse
Antibody Type Monoclonal
Isotype Mouse IgG2b
Immunogen Pigeon cytochrome c
Appearance Colorless liquid
Concentration 1 mg/ml
Formulation In PBS, pH 7.2 containing 50% glycerol and 0.09% sodium azide
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot
Application & Usage Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects a 12.0 kDa protein corresponding to the apparent molecular weight of cytochrome c.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Cytochrome c (m.w. 12,500) is an electron transport protein from mitochondria. It is released from mitochondria to cytoplasm during the early stages of apoptosis, prior to caspase activation, DNA fragmentation, and loss of membrane potential. The cytoplasmic cytochrome c is associated with Apaf-1 and caspase-9 to activate caspase-3 and other caspases.

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Liang, N. et. al. Steroidogenic Factor-1 Is Requipurple for TGF-β3-Mediated 17β-Estradiol Synthesis in Mouse Ovarian Granulosa Cells. Endocrinology, Aug 2011; 152: 3213 - 3225.
Chen J. et al. (2007) Stem Cells 10.1634/stemcells.2007-0098.
Jones GJ et al. (2007) J. Neurosci. 27:3703-37121.
Machiya J-I et al. (2007) Am. J. Respir. Cell Mol. Biol. 36: 428-426.
Turpin, S.M. et al. (2006) Am. J. Physiol Endorinol. Metab. 291: E1341 - E1350.
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