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Cytochrome c Antibody

based on 8 citations in multiple journalsCytochrome c Antibody84.1 4
Catalog #: 3025
SKU-Size Size Price Qty
3025-30T 30 µg
$89.00
3025-100 100 µg
$290.00
More Sizes Get Quote

Product Details

Antibody Target Cytochrome c
Alternate Name CYCS, CYC
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide corresponding to residues surrounding amino acid 70 of rat cytochrome c
Accession # NP_036972
Gene ID 25310
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation In phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
Purification Affinity purified
Species Reactivity Human, Mouse, Rat, Bovine, Chicken, Dog
Application Western blot, Immunoprecipitation
Application & Usage Western blotting (0.5-4 µg/ml) and immunoprecipitation (10-20 µg/ml). The cytochrome c antibody detects the 12.6 kDa cytochrome c from human, mouse, and rat samples. Jurkat cell lysate, NIH3T3 cell lysate, and rat kidney tissue lysate can be used as posit
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cytochrome c (m.w. 12,500) is an electron transport protein from mitochondria. It is released from mitochondria to cytoplasm during the early stages of apoptosis, prior to caspase activation, DNA fragmentation, and loss of membrane potential. The cytoplasmic cytochrome c is associated with Apaf-1 and caspase-9 to activate caspase-3 and other caspases


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Chen J et al. (2008) Stem Cells: 26: 135-145.
Crowe S et al (2008) Endocrinology 149: 2546-2556.
Husain S-R A et al. (2008) Blood 10.1182/blood02007-10-115733.
Lan L et al (2008) J. Immunol. 181: 4926 - 4935.
Zhao J et al (2008) Cancer Res. 68: 4133 - 4141.
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