Cyclosporine A

An immunosuppressant

WARNING: This product can expose you to chemicals including Cyclosporin A, which is [are] known to the State of California to cause cancer. For more information go to

Cyclosporine A is available from Abcam as ab120114.
Catalog #: 1522 | abID:

Product Details

Alternate Name Antibiotic S 7481F1, Cyclosporine
Appearance White solid
CAS # 59865-13-3
Molecular Formula C₆₂H₁₁₁N₁₁O₁₂
Molecular Weight 1202.6
Purity >99%
Solubility DMSO and EtOH
InChi InChI=1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50+,51+,52-/m1/s1
PubChem CID 5284373
MDL Number MFCD00274558
Handling Protect from light and air
Storage Conditions 4°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.


A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B. Cyclosporin A and its derivatives (including Alisporivir) inhibit multiple coronaviruses. Cyclosporin A and its derivatives (including Alisporivir) inhibit multiple coronaviruses.

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