Product Details
| Alternate Name | Antibiotic S 7481F1, Cyclosporine |
|---|---|
| Appearance | White solid |
| CAS # | 59865-13-3 |
| Molecular Formula | C₆₂H₁₁₁N₁₁O₁₂ |
| Molecular Weight | 1202.6 |
| Purity | >99% |
| Solubility | DMSO and EtOH |
| SMILES | CCC1C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)CC=CC)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C |
| InChi | InChI=1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50+,51+,52-/m1/s1 |
| InChi Key | PMATZTZNYRCHOR-CGLBZJNRSA-N |
| PubChem CID | 5284373 |
| MDL Number | MFCD00274558 |
| Handling | Protect from light and air |
| Storage Conditions | 4°C |
| Shipping Conditions | RT |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B. Cyclosporin A and its derivatives (including Alisporivir) inhibit multiple coronaviruses. Cyclosporin A and its derivatives (including Alisporivir) inhibit multiple coronaviruses.
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