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Cyclic-di-GMP

A STING ligand
Catalog #: B2045
SKU-Size Size Price Qty
B2045-250 250 μg
$145.00
B2045-1000 1 mg
$465.00
More Sizes Get Quote

Product Details

Alternate Name Guanylyl-(3'→5')-3'-guanylic acid, cyclic nucleotide; Cyclic diguanylate; 3',5'-Cyclic diguanylic acid; c-di-GMP
Appearance White to off-white solid
CAS # 61093-23-0
Molecular Formula C₂₀H₂₄N₁₀O₁₄P₂
Molecular Weight 690.41
Purity ≥95%
Solubility H₂O (1 mg/ml)
SMILES C1C2C(C(C(O2)N3C=NC4=C3NC(=NC4=O)N)O)OP(=O)(OCC5C(C(C(O5)N6C=NC7=C6NC(=NC7=O)N)O)OP(=O)(O1)O)O
InChi InChI=1S/C20H24N10O14P2/c21-19-25-13-7(15(33)27-19)23-3-29(13)17-9(31)11-5(41-17)1-39-45(35,36)44-12-6(2-40-46(37,38)43-11)42-18(10(12)32)30-4-24-8-14(30)26-20(22)28-16(8)34/h3-6,9-12,17-18,31-32H,1-2H2,(H,35,36)(H,37,38)(H3,21,25,27,33)(H3,22,26,28,34)/t5-,6-,9-,10-,11-,12-,17-,18-/m1/s1
InChi Key PKFDLKSEZWEFGL-MHARETSRSA-N
PubChem CID 6323195
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cyclic di-GMP (c-di-GMP) is one of the most important and common bacterial second messenger. It is involved in numerous prokaryotic processes, including biofilm formation, motility, virulence, and cell cycling. c-di-GMP also has functions in eukaryotic cells. It is detected by the transmembrane protein stimulator of interferon genes (STING), leading to activation of the innate immune system.


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