Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

CXCR4 Antibody

based on 1 citations in multiple journalsCXCR4 Antibody14.1 4
Catalog #: 5541
SKU-Size Size Price Qty
5541-30T 30 µg
$89.00
5541-100 100 µg
$265.00
More Sizes Get Quote

Product Details

Antibody Target CXCR4
Alternate Name CXCR-4, CXCR4, CXCR 4,CXCR4 Polyclonal Antibody, Anti-CXCR4 Polyclonal antibody, CXCR4 antibody, Anti-CXCR4, CXCR, CD4, SDF, HIV-2, Fusin
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide surrounding amino acid 18 of mouse CXCR4
Accession # P70658
Gene ID 12767
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation Supplied in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.03% proclin
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot
Application & Usage Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Blocking peptide (Cat.# 5541BP-50) is available separately.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

CXCR4 (fusin) is a member in the seven-transmembrane domain G-protein-coupled chemokine receptor family. The full-length cDNA was isolated from a human spleen cDNA library. Its ligand is chemokine stroma-derived factor (SDF). CXCR4 has been shown to be the co-receptor for HIV-1 binding to CD4 throμgh the viral envelope glycoprotein gp120. In other cases, CXCR4 can function as the only receptor for the interaction of HIV-2 with CD4 and host cells. A mouse monoclonal antibody (12G5) to CXCR4 has been shown to inhibit HIV infectivity and HIV-induced syncytium.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.
Tillmanns J et al. (2008) PNAS 105: 1668-1673.
For more citations of this product click here