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CXCL2, human recombinant

Suppresses hematopoietic progenitor cell proliferation
Catalog #: 7306
$295.00

Product Details

Cat # +Size 7306-100
Size 100 μg
Alternate Name C-X-C motif chemokines 2, MIP2-alpha, Gro-beta, CINC-2a, GRO2, GROb, MIP2, MIP2A, SCYB2
Gene Symbol CXCL2
Gene ID 2920
Accession # P19875
Source E. coli
Appearance Liquid
Physical Form Description 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0).
Molecular Weight 10.1 kDa (94 aa, 35-107 aa + His tag), confirmed by MALDI-TOF.
Purity by SDS-PAGE ≥95%
Endotoxin Level < 1.0 EU per 1 microgram of protein
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MAPLATELRC QCLQTLQGIH LKNIQSVKVK SPGPHCAQTE VIATLKNGQK ACLNPASPMV KKIIEKMLKN GKSN
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

CXCL2 is a small cytokine belonging to the CXC chemokine family that is also known as Chemokine (C-X-C motif) ligand 2, and macrophage inflammatory protein 2-alpha (MIP2-alpha). CXCL2 is secreted by activated monocytes, neutrophils and macrophages and expressed at sites of inflammation. CXCL2 is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells and suppresses hematopoietic progenitor cell proliferation. Recombinant human CXCL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.


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