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CST6, human recombinant

A secretable proteins that influence osteogenesis, regulates insulin and hepatocyte growth factor receptors, and the response to systemic inflammation.
Catalog #: 9234

In stock

SKU-Size Size Price Qty
9234-10 10 µg
$145.00
9234-50 50 µg
$365.00
More Sizes Get Quote

Product Details

Alternate Name Cystatin-M, Cystatin E/M
Gene Symbol CST6
Gene ID 1474
Accession # NP_001314
Source E.coli
Appearance Liquid
Physical Form Description Liquid
Molecular Weight This protein is fused with a 6× His tag at N-terminus and has a calculated MW of 15.9 kDa.
Purity by SDS-PAGE ≥90%
Purity by ≥90%
Biological Activity IC50 value is < 10nM
Reconstitution Instructions In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl..
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MRPQERMVGE LRDLSPDDPQ VQKAAQAAVA SYNMGSNSIY YFRDTHIIKA QSQLVAGIKY FLTMEMGSTD CRKTRVTGDH VDLTTCPLAA GAQQEKLRCD FEVLVVPWQN SSQLLKHNCV QM
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

CST6 is a member of the type 2 cystatin family. Some of the members are active cysteine protease inhibitors, while cystatin E/M moderate the inhibition of cathepsin B but is not active against cathepsin C. CST6 is secretable proteins that influence osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors, and the response to systemic inflammation.


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