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Product Details
| Alternate Name | 1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl[1,2-b]furan-10,11-dione |
|---|---|
| Appearance | Orange solid |
| CAS # | 35825-57-1 |
| Molecular Formula | C₁₉H₂₀O₃ |
| Molecular Weight | 296.36 |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (~ 5 mg/ml) |
| SMILES | CC1COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C |
| InChi | InChI=1S/C19H20O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,10H,4-5,8-9H2,1-3H3/t10-/m0/s1 |
| InChi Key | GVKKJJOMQCNPGB-JTQLQIEISA-N |
| PubChem CID | 160254 |
| MDL Number | MFCD07636810 |
| Handling | Protect from light and air |
| Storage Conditions | -20 ̊C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Cryptotanshinone is a natural product isolated from the roots of Salvia miltiorrhiza Bunge that displays a variety of biological activities. Displays antitumor activity by inhibition of STAT3 (IC₅₀ = 4.6 µM). Also displays antibacterial and anti-inflammatory activity and acts as an antidiabetes and antiobesity agent via activation of AMP-activated protein kinase (AMPK). Also inhibits acetylcholinesterase (AChE) (IC₅₀ = 4.09 μM) and reduction in Aβ peptide generation.
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