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Cryptotanshinone

A STAT3 inhibitor
Catalog #: 2429
SKU-Size Size Price Qty
2429-5 5 mg
$75.00
2429-25 25 mg
$295.00
More Sizes Get Quote

Product Details

Alternate Name 1,2,6,7,8,9-Hexahydro-1,6,6-trimeth​yl[1,2-b]furan-10,11-dione
Appearance Orange solid
CAS # 35825-57-1
Molecular Formula C₁₉H₂₀O₃
Molecular Weight 296.36
Purity ≥98% by HPLC
Solubility DMSO (~ 5 mg/ml)
SMILES CC1COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C
InChi InChI=1S/C19H20O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,10H,4-5,8-9H2,1-3H3/t10-/m0/s1
InChi Key GVKKJJOMQCNPGB-JTQLQIEISA-N
PubChem CID 160254
MDL Number MFCD07636810
Handling Protect from light and air
Storage Conditions -20 ̊C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cryptotanshinone is a natural product isolated from the roots of Salvia miltiorrhiza Bunge that displays a variety of biological activities. Displays antitumor activity by inhibition of STAT3 (IC₅₀ = 4.6 µM). Also displays antibacterial and anti-inflammatory activity and acts as an antidiabetes and antiobesity agent via activation of AMP-activated protein kinase (AMPK). Also inhibits acetylcholinesterase (AChE) (IC₅₀ = 4.09 μM) and reduction in Aβ peptide generation.


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