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A BET bromodomain inhibitor
Catalog #: 9404
SKU-Size Size Price Qty
9404-1 1 mg
9404-5 5 mg
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Product Details

Alternate Name (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide
Appearance White solid
CAS # 1446144-04-2
Molecular Formula C₁₉H₁₈ClN₅OS
Molecular Weight 399.9
Purity ≥98% by HPLC
Solubility DMSO (>35 mg/ml)
InChi InChI=1S/C19H18ClN5OS/c1-9-10(2)27-19-16(9)17(12-4-6-13(20)7-5-12)22-14(8-15(21)26)18-24-23-11(3)25(18)19/h4-7,14H,8H2,1-3H3,(H2,21,26)/t14-/m0/s1
PubChem CID 71291068
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


CPI-203 is an analog of (+)-JQ1 (Cat. No. 2070). Acts as a BET bromodomain inhibitor. It is comparable or superior to (+)-JQ1 in inhibiting BRD4 binding and action in vitro or in cells.CPI-203 arrests the growth of leukemic T cells in vitro (EC₅₀ = 91 nM) and rapidly suppresses leukemia burden in mice.

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