Product Details
| Alternate Name | Tasocitinib; Tofacitinib |
|---|---|
| Appearance | Off-white to pale yellow solid |
| CAS # | 477600-75-2 |
| Molecular Formula | C₁₆H₂₀N₆O |
| Molecular Weight | 312.37 |
| Purity | ≥99% by HPLC |
| Solubility | DMSO (100 mg/ml) of EtOH (100 mg/ml) |
| SMILES | CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N |
| InChi | InChI=1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20) |
| InChi Key | UJLAWZDWDVHWOW-UHFFFAOYSA-N |
| PubChem CID | 9818231 |
| MDL Number | MFCD11616529 |
| Handling | Protect from air and moisture |
| Storage Conditions | -20°C |
| Shipping Conditions | RT |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Cell-permeable. A Janus Kinase 3 (JAK3) inhibitor. Displays greater antiproliferative and pro-apoptotic activity against murine multipotent factor-dependent cell Patersen-erythropoietin receptor (FDCP-EpoR) cells harboring JAK2(V617F) compared with JAK2(WT).
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