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CP-690550

A JAK3 inhibitor
Catalog #: 1622

In stock

SKU-Size Size Price Qty
1622-5 5 mg
$150.00
1622-25 25 mg
$520.00
More Sizes Get Quote

Product Details

Alternate Name Tasocitinib; Tofacitinib
Appearance Off-white to pale yellow solid
CAS # 477600-75-2
Molecular Formula C₁₆H₂₀N₆O
Molecular Weight 312.37
Purity ≥99% by HPLC
Solubility DMSO (100 mg/ml) of EtOH (100 mg/ml)
SMILES CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N
InChi InChI=1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)
InChi Key UJLAWZDWDVHWOW-UHFFFAOYSA-N
PubChem CID 9818231
MDL Number MFCD11616529
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Cell-permeable. A Janus Kinase 3 (JAK3) inhibitor. Displays greater antiproliferative and pro-apoptotic activity against murine multipotent factor-dependent cell Patersen-erythropoietin receptor (FDCP-EpoR) cells harboring JAK2(V617F) compared with JAK2(WT).


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