It is a class I and class II histone deacetylase (HDAC) inhibitor
Catalog #: B2805 | abID:

Product Details

Alternate Name Coumarin-suberoylanilide hydroxamic acid, N1-Hydroxy-N8-(4-methyl-2-oxo-2H-chromen-7-yl)octanediamide
Appearance Crystalline solid
CAS # 1260635-77-5
Molecular Formula C₁₈H₂₂N₂O₅
Molecular Weight 346.38
Purity ≥98%
Solubility ~5 mg/ml in DMSO and DMF
InChi InChI=1S/C18H22N2O5/c1-12-10-18(23)25-15-11-13(8-9-14(12)15)19-16(21)6-4-2-3-5-7-17(22)20-24/h8-11,24H,2-7H2,1H3,(H,19,21)(H,20,22)
PubChem CID 53393956
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.


Suberoylanilide hydroxamic acid (SAHA) is a class I and class II histone deacetylase (HDAC) inhibitor. It is a fluorescent probe that competitively binds HDAC. It is a SAHA derivative where the anilino “cap” group is replaced by 7-amino-4-methylcoumarin. The fluorescence excitation and emission maxima of free c-SAHA is 325 and 400 nm, respectively. Fluorescence is quenched by 50% when bound to HDAC8.

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