Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Coumarin-SAHA

It is a class I and class II histone deacetylase (HDAC) inhibitor
Catalog #: B2805
SKU-Size Size Price Qty
B2805-1 1 mg
$55.00
B2805-5 5 mg
$195.00
More Sizes Get Quote

Product Details

Alternate Name Coumarin-suberoylanilide hydroxamic acid, N1-Hydroxy-N8-(4-methyl-2-oxo-2H-chromen-7-yl)octanediamide
Appearance Crystalline solid
CAS # 1260635-77-5
Molecular Formula C₁₈H₂₂N₂O₅
Molecular Weight 346.38
Purity ≥98%
Solubility ~5 mg/ml in DMSO and DMF
SMILES CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)CCCCCCC(=O)NO
InChi InChI=1S/C18H22N2O5/c1-12-10-18(23)25-15-11-13(8-9-14(12)15)19-16(21)6-4-2-3-5-7-17(22)20-24/h8-11,24H,2-7H2,1H3,(H,19,21)(H,20,22)
InChi Key YSRCADVJNRJJAV-UHFFFAOYSA-N
PubChem CID 53393956
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Suberoylanilide hydroxamic acid (SAHA) is a class I and class II histone deacetylase (HDAC) inhibitor. It is a fluorescent probe that competitively binds HDAC. It is a SAHA derivative where the anilino “cap” group is replaced by 7-amino-4-methylcoumarin. The fluorescence excitation and emission maxima of free c-SAHA is 325 and 400 nm, respectively. Fluorescence is quenched by 50% when bound to HDAC8.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.