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Conessine

A specific antagonist of histamine H3 receptors
Catalog #: B2772
SKU-Size Size Price Qty
B2772-10 10 mg
$65.00
B2772-50 50 mg
$255.00
More Sizes Get Quote

Product Details

Alternate Name Neriine; (3β)-N,N-dimethyl-con-5-enin-3-amine; Roquessine; NSC 119994
Peptide Sequence N/A
Appearance White to off-white solid
CAS # 546-06-5
Molecular Formula C₂₄H₄₀N₂
Molecular Weight 356.59
Purity ≥97%
Solubility >10 mg/ml DMSO, >10 mg/ml Ethanol
SMILES CC1C2CCC3C2(CCC4C3CC=C5C4(CCC(C5)N(C)C)C)CN1C
InChi InChI=1S/C24H40N2/c1-16-20-8-9-22-19-7-6-17-14-18(25(3)4)10-12-23(17,2)21(19)11-13-24(20,22)15-26(16)5/h6,16,18-22H,7-15H2,1-5H3/t16-,18-,19+,20+,21-,22-,23-,24-/m0/s1
InChi Key GPLGAQQQNWMVMM-MYAJQUOBSA-N
PubChem CID 441082
MDL Number MFCD00016752
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Conessine is a plant steroid alkaloid that acts as a potent and specific antagonist of histamine H3 receptors. Conessine is 1860-fold selective for H3 over H4 and does not bind to H1 or H2 receptors. It also binds to the human α2C4 adrenergic receptor (pKi = 7.98).


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