Compound 401

A DNA-PK inhibitor
Catalog #: 1657 | abID:

Product Details

Cat # +Size 1657-5
Size 5 mg
Alternate Name 2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one
Appearance White to off-white solid
CAS # 168425-64-7
Molecular Formula C₁₆H₁₅N₃O₂
Molecular Weight 281.31
Purity ≥97% by HPLC
Solubility DMSO (10 mM) or EtOH (5 mM)
SMILES C1COCCN1C2=CC(=O)N3C=CC4=CC=CC=C4C3=N2
InChi InChI=1S/C16H15N3O2/c20-15-11-14(18-7-9-21-10-8-18)17-16-13-4-2-1-3-12(13)5-6-19(15)16/h1-6,11H,7-10H2
InChi Key BVRDQVRQVGRNHG-UHFFFAOYSA-N
PubChem CID 10039361
MDL Number MFCD10568147
Handling Protect from air and light
Storage Conditions 4°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Cell-permeable. A reversible and selective inhibitor of DNA-dependent protein kinase (DNA-PK) (IC₅₀ = 0.28 µM) that also targets mTOR (IC₅₀ = 5. 3µM), but not PI 3-K in vitro. Induces apoptosis in vitro.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.