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Compound 112254

An adiponectin receptor agonist
Catalog #: 2573
SKU-Size Size Price Qty
2573-5 5 mg
$125.00
2573-25 25 mg
$495.00
More Sizes Get Quote

Product Details

Alternate Name 4-(tert-Butyl)-N-(3-(4-(4-methoxybenzyl)piperazin-1-yl)-3-oxopropyl)benzamide
Appearance White solid
Molecular Formula C₂₆H₃₅N₃O₃
Molecular Weight 437.57
Purity ≥98% by NMR
Solubility DMSO or EtOH
SMILES CC(C1=CC=C(C=C1)CNCCCN2CCN(CC3=CC=C(OC)C=C3)CC2)(C)C
InChi InChI=1S/C26H39N3O/c1-26(2,3)24-10-6-22(7-11-24)20-27-14-5-15-28-16-18-29(19-17-28)21-23-8-12-25(30-4)13-9-23/h6-13,27H,5,14-21H2,1-4H3
InChi Key LUEVKMSIYRYUKC-UHFFFAOYSA-N
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

An adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 less potent than AdipoRon (Cat. Nos. 2565 & 2572). Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells .Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms.


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