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Complement Component C1q, Human Serum

A critical component of the classical complement system
Catalog #: P1721
$745.00

Product Details

Cat # +Size P1721-1000
Size 1 mg
Gene ID Chain A - 712; Chain B - 713; Chain C - 714
Accession # Chain A - P02745; Chain B - P02746; Chain C - P02747
Source Human serum
Appearance Lyophilized protein
Physical Form Description Lyophilized powder
Purity by SDS-PAGE ≥ 96%
Reconstitution Instructions Reconstitute to desired concentration in sterile deionized water.
Handling Centrifuge the vial prior to opening.
Storage Conditions 4.0 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Complement subcomponent C1q is composed of three polypeptide chains (A, B, and C). C1q associates with C1r and C1s to set up the first component of the serum complement system. Activation of the complement system is induced by interaction with the Fc regions of IgG or IgM antibodies within immune complexes, enhancing the ability of those antibodies and cells of the immune system to attack pathogens. C1q deficiency is associated with lupus and glomerulonephritis.


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