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Complement C1q, Human Plasma (High Salt Buffer with Glycerol)

A critical component of the classical complement system
Catalog #: P1743
SKU-Size Size Price Qty
P1743-500 500 μg
$345.00
P1743-1000 1 mg
$545.00
More Sizes Get Quote

Product Details

Alternate Name C1q; C1QA; C1QB; C1QC; Complement Component 1, Q Subcomponent
Gene ID Chain A - 712; Chain B - 713; Chain C - 714
Accession # Chain A - P02745; Chain B - P02746; Chain C - P02747
Source Human plasma
Appearance Sterile Filtered colorless solution
Physical Form Description Liquid
Purity by SDS-PAGE > 98%
Formulation 10 mM HEPES, 300 mM NaCl, pH 7.2, with 40% glycerol
Handling Centrifuge the vial prior to opening.
Storage Conditions -70 °C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not For Use in Humans.

Details

Complement subcomponent C1q is composed of three polypeptide chains (A, B, and C). C1q associates with C1r and C1s to set up the first component of the serum complement system. Activation of the complement system is induced by interaction with the Fc regions of IgG or IgM antibodies within immune complexes, enhancing the ability of those antibodies and cells of the immune system to attack pathogens. C1q deficiency is associated with lupus and glomerulonephritis.


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