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Product Details
| Alternate Name | Belcomycine; Colistin sulfate salt; EBD44330; MFCD00146495; N-[3-Amino-1-[[1-[[3-amino-1-[[6,9,18-tris(2-aminoethyl)-3-(1-hydroxyethyl)-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]carbamoyl]propyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]propyl]-5-methyl-heptanamide sulfate; Polymyxin E; Colimycin |
|---|---|
| Appearance | White to off-white solid |
| CAS # | 1264-72-8 |
| Molecular Formula | C₅₂H₁₀₀N₁₆O₁₇S |
| Molecular Weight | 1253.51 |
| Purity | ≥98% by TLC |
| Solubility | H₂O (50 mg/ml) |
| SMILES | CCC(C)CCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CCN)CC(C)C)CC(C)C)CCN)CCN)C(C)O.OS(=O)(=O)O |
| InChi | InChI=1S/C52H98N16O13.H2O4S/c1-9-29(6)11-10-12-40(71)59-32(13-19-53)47(76)68-42(31(8)70)52(81)64-35(16-22-56)44(73)63-37-18-24-58-51(80)41(30(7)69)67-48(77)36(17-23-57)61-43(72)33(14-20-54)62-49(78)38(25-27(2)3)66-50(79)39(26-28(4)5)65-45(74)34(15-21-55)60-46(37)75;1-5(2,3)4/h27-39,41-42,69-70H,9-26,53-57H2,1-8H3,(H,58,80)(H,59,71)(H,60,75)(H,61,72)(H,62,78)(H,63,73)(H,64,81)(H,65,74)(H,66,79)(H,67,77)(H,68,76);(H2,1,2,3,4) |
| InChi Key | VEXVWZFRWNZWJX-UHFFFAOYSA-N |
| PubChem CID | 86278104 |
| MDL Number | MFCD00146495 |
| Handling | Protect from air and moisture |
| Storage Conditions | 4°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Colistin sulfate is a potent cationic peptide antibiotic of the polymyxin family that binds to lipids on the cell cytoplasmic membrane of Gram-negative
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