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CZC24832

A selective PI3K-γ inhibitor
Catalog #: B1676

In stock

SKU-Size Size Price Qty
B1676-5 5 mg
$115.00
B1676-25 25 mg
$450.00
More Sizes Get Quote

Product Details

Alternate Name CZC24832; CZC 24832; CZC-24832; 5-(2-amino-8-fluoro-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-tert-butylpyridine-3-sulfonamide
Appearance Solid
CAS # 1159824-67-5
Molecular Formula C₁₅H₁₇FN₆O₂S
Molecular Weight 364.4
Purity >98%
Solubility DMSO
SMILES CC(C)(C)NS(=O)(=O)C1=CN=CC(=C1)C2=CN3C(=NC(=N3)N)C(=C2)F
InChi InChI=1S/C15H17FN6O2S/c1-15(2,3)21-25(23,24)11-4-9(6-18-7-11)10-5-12(16)13-19-14(17)20-22(13)8-10/h4-8,21H,1-3H3,(H2,17,20)
InChi Key RXRZPHQBTHQXSV-UHFFFAOYSA-N
PubChem CID 42623951
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

CZC24832 is a selective inhibitor of PI 3-kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay); exhibits limited off-target effects in kinome profiling of 154 identified lipid and protein kinases and 922 other proteins.


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