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Clioquinol

A proteasome inhibitor and an anticancer agent
Catalog #: 2454
SKU-Size Size Price Qty
2454-1G 1 g
$65.00
2454-5G 5 g
$155.00
More Sizes Get Quote

Product Details

Alternate Name 5-Chloro-8-hydroxy-7-iodoquinoline, 5-chloro-7-iodo-8-quinolinol; CQ
Appearance Tan solid
CAS # 130-26-7
Molecular Formula C₉H₅CIlNO
Molecular Weight 305.5
Purity ≥95% by HPLC
Solubility DMSO (>25 mg/ml)
SMILES C1=CC2=C(C(=C(C=C2Cl)I)O)N=C1
InChi InChI=1S/C9H5ClINO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H
InChi Key QCDFBFJGMNKBDO-UHFFFAOYSA-N
PubChem CID 2788
MDL Number MFCD00006787
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

An antiparasitic agent that forms stable complexes with copper and used for treatment of Alzheimer’s disease. Displays anticancer properties by inhibition of proteasome activity. It targets tumor proteasome in vivo in a copper-dependent manner, resulting in formation of an active AR (androgen receptor) inhibitor and apoptosis inducer that is responsible for its observed antiprostate tumor effect.


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