Product Details
| Alternate Name | A-56268, 6-O-methyl-erythromycin, TE 031, Antibiotic A 56268 |
|---|---|
| Appearance | White to off-white solid |
| CAS # | 81103-11-9 |
| Molecular Formula | C₃₈H₆₉NO₁₃ |
| Molecular Weight | 747.95 |
| Purity | ≥98% |
| Solubility | ~ 1 mg/ml DMSO |
| SMILES | CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)OC)C)C)O)(C)O |
| InChi | InChI=1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1 |
| InChi Key | AGOYDEPGAOXOCK-KCBOHYOISA-N |
| PubChem CID | 84029 |
| MDL Number | MFCD00865140 |
| Handling | Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure. |
| Storage Conditions | -20ºC |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Clarithromycin is a semisynthetic macrolide antibiotic derived from erythromycin. It inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation. Clarithromycin may be used to attenuate cardiac transplantation rejection via matrix metalloproteinase suppression. Clarithromycin has been used to study inflammatory markers in chronic obstructive pulmonary disease (COPD).
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