A semisynthetic macrolide antibiotic
Catalog #: B2692 | abID:

Product Details

Alternate Name A-56268, 6-O-methyl-erythromycin, TE 031, Antibiotic A 56268
Appearance White to off-white solid
CAS # 81103-11-9
Molecular Formula C₃₈H₆₉NO₁₃
Molecular Weight 747.95
Purity ≥98%
Solubility ~ 1 mg/ml DMSO
InChi InChI=1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
PubChem CID 84029
MDL Number MFCD00865140
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Clarithromycin is a semisynthetic macrolide antibiotic derived from erythromycin. It inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation. Clarithromycin may be used to attenuate cardiac transplantation rejection via matrix metalloproteinase suppression. Clarithromycin has been used to study inflammatory markers in chronic obstructive pulmonary disease (COPD).

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