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Cladribine

An adenosine deaminase inhibitor
Catalog #: B2037

In stock

SKU-Size Size Price Qty
B2037-5 5 mg
$75.00
B2037-25 25 mg
$275.00
More Sizes Get Quote

Product Details

Alternate Name 2-Chloro-2'-deoxy-adenosine; NSC105014; RWJ 26251
Appearance White to off-white solid
CAS # 4291-63-8
Molecular Formula C₁₀H₁₂ClN₅O₃
Molecular Weight 285.7
Purity ≥98% by HPLC
Solubility DMSO (~10 mg/ml)
SMILES C1C(C(OC1N2C=NC3=C2N=C(N=C3N)Cl)CO)O
InChi InChI=1S/C10H12ClN5O3/c11-10-14-8(12)7-9(15-10)16(3-13-7)6-1-4(18)5(2-17)19-6/h3-6,17-18H,1-2H2,(H2,12,14,15)/t4-,5+,6+/m0/s1
InChi Key PTOAARAWEBMLNO-KVQBGUIXSA-N
PubChem CID MFCD00153939
MDL Number 20279
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cladribine is an adenosine deaminase inhibitor. It is phosphorylated by deoxycytidine kinase, resulting in its intracellular accumulation and inhibition of ribonucleotide reductase. Cladribine displays selective cytotoxicity against both proliferating and non-dividing lymphocytes. Also displays immunosuppressive activity.


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