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Citarinostat

A potent, selective and orally available histone deacetylase 6 (HDAC6) inhibitor
Catalog #: B1560
SKU-Size Size Price Qty
B1560-5 5 mg
$135.00
B1560-25 25 mg
$535.00
More Sizes Get Quote

Product Details

Alternate Name 2-((2-chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide; ACY-241
Appearance Crystalline solid
CAS # 1316215-12-9 
Molecular Formula C₂₄H₂₆ClN₅O₃
Molecular Weight 467.95
Purity ≥98% by HPLC
Solubility DMSO (>30 mg/ml)
SMILES C1=CC=C(C=C1)N(C2=CC=CC=C2Cl)C3=NC=C(C=N3)C(=O)NCCCCCCC(=O)NO
InChi InChI=1S/C24H26ClN5O3/c25-20-12-7-8-13-21(20)30(19-10-4-3-5-11-19)24-27-16-18(17-28-24)23(32)26-15-9-2-1-6-14-22(31)29-33/h3-5,7-8,10-13,16-17,33H,1-2,6,9,14-15H2,(H,26,32)(H,29,31)
InChi Key VLIUIBXPEDFJRF-UHFFFAOYSA-N
PubChem CID 53340426
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Citarinostat (ACY-241), is a potent, selective and orally available histone deacetylase 6 (HDAC6) inhibitor with IC₅₀ values of 4 nM and 76 nM for HDAC6 and HDAC3, respectively. Displays antineoplastic activity.


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