Product Details
| Alternate Name | cis-Dichlorodiammine platinum(II), cis-Platinum(II) diammine dichloride, Cis-Diamineplatinum (II) dichloride |
|---|---|
| Appearance | Yellow soild |
| CAS # | 15663-27-1 |
| Molecular Formula | Pt(NH₃)₂Cl₂ |
| Molecular Weight | 300.05 |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (10 mg/ml) |
| SMILES | N.N.Cl[Pt+2]Cl |
| InChi | InChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+4/p-2 |
| InChi Key | BSJGASKRWFKGMV-UHFFFAOYSA-L |
| PubChem CID | 441203 |
| MDL Number | MFCD00011623 |
| Handling | Protect from light and moisture |
| Storage Conditions | RT |
| Shipping Conditions | RT |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
A platinum coordination complex with potent anti-neoplastic activity.
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Tanay Thakar, Ubiquitinated-PCNA protects replication forks from DNA2-mediated degradation by regulating Okazaki fragment maturation and chromatin assembly. Nat Commun., May 2020; 32358495.
Ramy Gadalla, Validation of CyTOF Against Flow Cytometry for Immunological Studies and Monitoring of Human Cancer Clinical Trials. Front Oncol, May 2019; 31165047.
Jianjun Peng, et al., ( 2018) si-TP73-AS1 suppressed proliferation and increased the chemotherapeutic response of GC cells to cisplatin, Oncology Letters, Sep. 2018, 30127981.
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