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A selective type III phosphodiesterase-3 (PDE3) inhibitor
Catalog #: 2560
SKU-Size Size Price Qty
2560-5 5 mg
2560-25 25 mg
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Product Details

Alternate Name N-Cyclohexyl-N-methyl-4-(1,2-dihydro-2-oxo-6-quinolyloxy)butyramide
Appearance White solid
CAS # 68550-75-4
Molecular Formula C₂₀H₂₆N₂O₃
Molecular Weight 342.44
Purity ≥98% by HPLC
Solubility DMSO (~30 mg/ml)
InChi InChI=1S/C20H26N2O3/c1-22(16-6-3-2-4-7-16)20(24)8-5-13-25-17-10-11-18-15(14-17)9-12-19(23)21-18/h9-12,14,16H,2-8,13H2,1H3,(H,21,23)
PubChem CID 2753
MDL Number MFCD00673958
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


A selective type III phosphodiesterase-3 (PDE3) inhibitor. Displays limited selectivity for PDE3A versus PDE3B (IC₅₀ = 27 and 50 nM). This inhibitory effect increases intracellular cAMP and inhibits platelet aggregation. Cilostamide also blocks PKB/Akt signaling pathway downstream via inhibition of Akt-activated PDE3B.

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