Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Cilostamide

A selective type III phosphodiesterase-3 (PDE3) inhibitor
Catalog #: 2560
SKU-Size Size Price Qty
2560-5 5 mg
$125.00
2560-25 25 mg
$495.00
More Sizes Get Quote

Product Details

Alternate Name N-Cyclohexyl-N-methyl-4-(1,2-dihydro-2-oxo-6-quinolyloxy)butyramide
Appearance White solid
CAS # 68550-75-4
Molecular Formula C₂₀H₂₆N₂O₃
Molecular Weight 342.44
Purity ≥98% by HPLC
Solubility DMSO (~30 mg/ml)
SMILES CN(C1CCCCC1)C(=O)CCCOC2=CC3=C(C=C2)NC(=O)C=C3
InChi InChI=1S/C20H26N2O3/c1-22(16-6-3-2-4-7-16)20(24)8-5-13-25-17-10-11-18-15(14-17)9-12-19(23)21-18/h9-12,14,16H,2-8,13H2,1H3,(H,21,23)
InChi Key UIAYVIIHMORPSJ-UHFFFAOYSA-N
PubChem CID 2753
MDL Number MFCD00673958
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A selective type III phosphodiesterase-3 (PDE3) inhibitor. Displays limited selectivity for PDE3A versus PDE3B (IC₅₀ = 27 and 50 nM). This inhibitory effect increases intracellular cAMP and inhibits platelet aggregation. Cilostamide also blocks PKB/Akt signaling pathway downstream via inhibition of Akt-activated PDE3B.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.