Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

CID-755673

A selective protein kinase D (PKD) inhibitor
Catalog #: 2660

In stock

SKU-Size Size Price Qty
2660-5 5 mg
$95.00
2660-25 25 mg
$375.00
More Sizes Get Quote

Product Details

Alternate Name 2,3,4,5-Tetrahydro-7-hydroxy-1H-benzofuro[2,3-c]azepin-1-one
Appearance Brown solid
CAS # 521937-07-5
Molecular Formula C₁₂H₁₁NO₃
Molecular Weight 217.22
Purity ≥98% by HPLC
Solubility DMSO (>20 mg/ml) or EtOH (~ 5 mg/ml)
SMILES C1CC2=C(C(=O)NC1)OC3=C2C=C(C=C3)O
InChi InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-12(15)11(8)16-10/h3-4,6,14H,1-2,5H2,(H,13,15)
InChi Key AACFPJSJOWQNBN-UHFFFAOYSA-N
PubChem CID 755673
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

CID-755673 is a selective small molecule inhibitor of protein kinase D (PKD) (IC₅₀s = 182, 280, 227 nM for PKD1, 2, and 3, respectively). It exhibits higher selectivity for PKD over Akt, polo-like kinase 1, CDK activating kinase, CAMKII and three different PKC isoforms (IC₅₀s range from 15 to > 50 µM). At 25 µM, CID-755673 has been shown to inhibit prostate cancer cell proliferation, cell migration, and invasion.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.