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CID-2011756

A protein kinase D (PKD) inhibitor
Catalog #: 2607
SKU-Size Size Price Qty
2607-5 5 mg
$95.00
2607-25 25 mg
$375.00
More Sizes Get Quote

Product Details

Alternate Name 5-(3-Chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-2-furancarboxamide
Appearance Off-white solid
CAS # 638156-11-3
Molecular Formula C₂₂H₂₁ClN₂O₃
Molecular Weight 396.87
Purity >98% by HPLC
Solubility DMSO (~ 18 mg/ml)
SMILES C1COCCN1CC2=CC=C(C=C2)NC(=O)C3=CC=C(O3)C4=CC(=CC=C4)Cl
InChi nChI=1S/C22H21ClN2O3/c23-18-3-1-2-17(14-18)20-8-9-21(28-20)22(26)24-19-6-4-16(5-7-19)15-25-10-12-27-13-11-25/h1-9,14H,10-13,15H2,(H,24,26)
InChi Key XQJWTJLJEYIUDZ-UHFFFAOYSA-N
PubChem CID 2011756
MDL Number MFCD04094273
Handling Protect from air and light
Storage Conditions -20 ̊C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cell-permeable. CID-2011756 is an ATP-competitive protein kinase D (PKD) inhibitor with IC₅₀ values of 0.6, 0.7 and 3.2 μM for PKD2, PKD3 and PKD1 respectively. Inhibits phorbol ester-induced endogenous PKD1 activation in LNCaP prostate cancer cells.


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