Product Details
| abID | ab142098 |
|---|---|
| Alternate Name | 4-(Acetylamino)-N-(2-aminophenyl)benzamide, Acetyldinaline, Gö 5549, PD 123654 |
| Appearance | White to off-white solid |
| CAS # | 112522-64-2 |
| Molecular Formula | C₁₅H₁₅N₃O₂ |
| Molecular Weight | 269.3 |
| Purity | ≥99% by HPLC |
| Solubility | DMSO (60 mg/ml) |
| SMILES | CC(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC=C2N |
| InChi | InChI=1S/C15H15N3O2/c1-10(19)17-12-8-6-11(7-9-12)15(20)18-14-5-3-2-4-13(14)16/h2-9H,16H2,1H3,(H,17,19)(H,18,20) |
| InChi Key | VAZAPHZUAVEOMC-UHFFFAOYSA-N |
| PubChem CID | 2746 |
| MDL Number | MFCD00866266 |
| Handling | Protect from air and moisture |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Cell-permeable. A histone deacetylase (HDAC) inhibitor (Ki values are 0.41, 0.75, >100 and >100 µM for HDAC1, HDAC3, HDAC6 and HDAC8 respectively). Displays significant antitumor activity in vitro and in vivo against a broad spectrum of murine and human tumor models.
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