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CHS-828

A Nampt/visfatin, NF-kB and IkB kinase inhibitor
Catalog #: 2044
SKU-Size Size Price Qty
2044-5 5 mg
$130.00
2044-25 25 mg
$495.00
More Sizes Get Quote

Product Details

Alternate Name GMX1778; (E)-1-[6-(4-Chlorophenoxy)hexyl]-2-cyano-3-(pyridin-4-yl)guanidine
Appearance White to off-white solid
CAS # 200484-11-3
Molecular Formula C₁₉H₂₂ClN₅O
Molecular Weight 371.86
Purity ≥98% by NMR
Solubility DMSO or EtOH
SMILES C1=CC(=CC=C1OCCCCCCN=C(NC#N)NC2=CC=NC=C2)Cl
InChi InChI=1S/C19H22ClN5O/c20-16-5-7-18(8-6-16)26-14-4-2-1-3-11-23-19(24-15-21)25-17-9-12-22-13-10-17/h5-10,12-13H,1-4,11,14H2,(H2,22,23,24,25)
InChi Key BOIPLTNGIAPDBY-UHFFFAOYSA-N
PubChem CID 148198
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A pyridyl cyanoguanidine derivative that displays potent antitumor activity. Also acts as an inhibitor of Nampt/visfatin, NF-kB and IkB kinase. In addition, CHS-828 induces programmed cell death and activates p53.


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