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CHIR 99021 trihydrochloride

A GSK-3β inhibitor
Catalog #: B1199
SKU-Size Size Price Qty
B1199-5 5 mg
B1199-25 25 mg
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Product Details

Alternate Name 6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile trihydrochloride; CT99022
Appearance Off-white solid
CAS # 1782235-14-6
Molecular Formula C₂₂H₁₈Cl₂N₈. 3HCl
Molecular Weight 574.72
Purity ≥98% by HPLC
Solubility DMSO (~25 mg/ml) or H₂O (>5 mg/ml)
SMILES CC1=CNC(C(C(C2=CC=C(Cl)C=C2Cl)=N3)=CN=C3NCCNC4=NC=C(C#N)C=C4)=N1.[H]Cl.[H]Cl.[H]Cl
InChi InChI=1S/C22H18Cl2N8.3ClH/c1-13-10-29-21(31-13)17-12-30-22(32-20(17)16-4-3-15(23)8-18(16)24)27-7-6-26-19-5-2-14(9-25)11-28-19;;;/h2-5,8,10-12H,6-7H2,1H3,(H,26,28)(H,29,31)(H,27,30,32);3*1H
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


CHIR99021 trihydrochloride is the hydrochloride salt of the potent and highly selective glycogen synthase kinase-3β (GSK-3β) inhibitor CHIR99021 (Cat. No. 1677).

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