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Chenodeoxycholic acid

A bile acid and FXR ligand
Catalog #: 2831
SKU-Size Size Price Qty
2831-1G 1 g
$65.00
2831-5G 5 g
$125.00
2831-25G 25 g
$395.00
More Sizes Get Quote

Product Details

Alternate Name CDCA; Fluibil; Hekbilin; Anthropodeoxycholic Acid; Kebilis; Ulmenide
Appearance White to off-white solid
CAS # 474-25-9
Molecular Formula C₂₄H₄₀O₄
Molecular Weight 392.57
Purity ≥95%
Solubility EtOH (50 mg/ml)
SMILES CC(CCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C
InChi C[[email protected]](CCC(=O)O)[[email protected]]1CC[[email protected]@H]2[[email protected]@]1(CC[[email protected]]3[[email protected]]2[[email protected]@H](C[[email protected]]4[[email protected]@]3(CC[[email protected]](C4)O)C)O)C
InChi Key RUDATBOHQWOJDD-BSWAIDMHSA-N
PubChem CID 10133
MDL Number MFCD00064142
Handling Hygroscopic
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Chenodeoxycholic acid (CDCA) is a hydrophobic primary bile acid that activates nuclear receptors involved in cholesterol metabolism. EC50 concentrations for activation of FXR (farnesoid X receptor) range from 13-34 μM. In cells, CDCA also binds to bile acid binding proteins (BABP) with a reported stoichiometery of 1:2.


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