Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]


A selective histone lysine methyltransferase (HKMT) inhibitor
Catalog #: 2283

Product Details

Cat # +Size 2283-500
Size 500 µg
Alternate Name (3S,3'S,5aR,5aR,10bR,10'bR,11aS,11'aS)­-2,2',3,3',5a,5'a,6,6'-octahydro-3,3'-bis(hydroxymethyl­)-2,2'-dimethyl-[10b,10'b(11H,11'H)-bi3,11a-epidithio­-11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole]-1,1',4­,4'-tetrone
Appearance Off-white solid
CAS # 28097-03-2
Molecular Formula C₃₀H₂₈N₆O₆S₄
Molecular Weight 696.84
Purity ≥95%
Solubility DMSO (~7 mg/ml)
InChi InChI=1S/C30H28N6O6S4/c1-33-21(39)27-11-25(15-7-3-5-9-17(15)31-19(25)35(27)23(41)29(33,13-37)45-43-27)26-12-28-22(40)34(2)30(14-38,46-44-28)24(42)36(28)20(26)32-18-10-6-4-8-16(18)26/h3-10,19-20,31-32,37-38H,11-14H2,1-2H3
PubChem CID 161591
MDL Number MFCD00133163
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


A fungal mycotoxin that inhibits the histone lysine methyltransferase (HKMT) SU(VAR)3-9 (IC₅₀ = 0.8 μM). Inhibits other Lys9-specific HMTs, including G9a (IC₅₀ = 2.5 μM) and DIM5 (IC₅₀ = 3 μM). Selectivity for Lys9-HMTs is indicated by higher IC₅₀ values (>90 μM) for Lys20-specific PRSET7, Lys27-specific EZH2, and Lys4-specific SET7/9.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.