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A potent, selective, ATP-competitive ALK inhibitor
Catalog #: 2867
SKU-Size Size Price Qty
2867-5 5 mg
2867-25 25 mg
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Product Details

Alternate Name 9-Ethyl-6,6-dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile; Alectinib; AF-802
Appearance White to off-white solid
CAS # 1256580-46-7
Molecular Formula C₃₀H₃₄N₄O₂
Molecular Weight 482.62
Purity ≥98% by HPLC
Solubility DMSO (2 mg/ml)
InChi InChI=1S/C30H34N4O2/c1-4-20-16-23-24(17-26(20)34-9-7-21(8-10-34)33-11-13-36-14-12-33)30(2,3)29-27(28(23)35)22-6-5-19(18-31)15-25(22)32-29/h5-6,15-17,21,32H,4,7-14H2,1-3H3
PubChem CID 49806720
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


CH5424802 is a potent, selective, ATP-competitive inhibitor of anaplastic lymphoma kinase (ALK) (IC₅₀ = 1.9 nM). It displays potent antitumor activity against RET-rearranged non-small cell lung cancer (NSCLC).

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