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cFMS Receptor Inhibitor IV

An inhibitor of cFMS/CSF-1R
Catalog #: B2922
SKU-Size Size Price Qty
B2922-5 5 mg
B2922-25 25 mg
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Product Details

Alternate Name cFMS Receptor Tyrosine Kinase Inhibitor; 5-cyano-N-(2,5-di(piperidin-1-yl)phenyl)furan-2-carboxamide; CSF-1 Receptor Inhibitor IV
Appearance Solid
CAS # 959626-45-0
Molecular Formula C₂₂H₂₆N₄O₂
Molecular Weight 378.47
Purity 97%
Solubility 5 mg/ml in DMSO
InChi InChI=1S/C22H26N4O2/c23-16-18-8-10-21(28-18)22(27)24-19-15-17(25-11-3-1-4-12-25)7-9-20(19)26-13-5-2-6-14-26/h7-10,15H,1-6,11-14H2,(H,24,27)
PubChem CID 28408236
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


cFMS Receptor Inhibitor IV is a furan carboxamide compound that is a potent, reversible, and ATP-competitive inhibitor of cFMS (Colony-stimulating Factor-1 Receptor) Tyrosine Kinase. It blocks cFMS autophosphorylation in CSF-1/M-CSF-stimulated HEK-293 cells and in cell-free in vitro kinase assays with IC₅₀ values of 76 nM and 17 nM respectively.

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