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CETP Antibody

Catalog #: 3413
SKU-Size Size Price Qty
3413-100 100 µg
$280.00
3413-30T 30 µg
$89.00
More Sizes Get Quote

Product Details

Antibody Target CETP
Alternate Name CETP Polyclonal, Anti-CETP, CETP, CETP antibody, HDL, cholesterol acyltransferase
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide corresponding to the C-terminus of human CETP
Accession # P11597
Gene ID 1071
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 μg (0.5 mg/ml) of antibody in PBS, pH 7.2, 30% glycerol, 0.5% BSA, 0.5 mM EDTA and 0.03% proclin
Purification Affinity purified
Species Reactivity Human, rat, rabbit
Application Western blot
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Jurkat cell lysate (Cat.# 2401-100) can be used as a positive control. The antibody recognizes 54 kDa CETP and the 70 kDa mature glycosylated form of CE
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

It has been proposed that high density lipoproteins (HDLs) function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.


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