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Ceruloplasmin, Human Plasma

Copper transport protein
Catalog #: P1452
$395.00

Product Details

Cat # +Size P1452-1
Size 1 mg
Alternate Name CER, CP, CP-2, Ferroxidase
Gene Symbol CP
Gene ID 1356
Accession # P00450
Source Human Plasma
Appearance Lyophilized powder
Physical Form Description Lyophilized
Molecular Weight 132,000
Purity by SDS-PAGE >95%
Reconstitution Instructions Reconstitute in De-ionized water
Handling Centrifuge the vial prior to opening.
Storage Conditions Store at -20°C. Once reconstituted store in aliquots at -20°C. Avoid repeated freeze-thaw cycles.
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Human Ceruloplasmin (CER) is officially known as ferroxidase or iron(II):oxygen oxidoreductase. CER is an enzyme synthesized in the liver containing 8 atoms of copper in its structure. Although Human CERULOPLASMIN (CER) is often considered a copper transport protein, this is not its primary function, just as human hemoglobin is not a carrier of iron, although it contains iron.
The main carrier for copper in the plasma of humans is albumin. Ceruloplasmin enzyme (ferroxidase) catalyzes the oxidation of ferrous iron (Fe2+) to ferric iron (Fe3+), therefore assisting in Human Ceruloplasmin enzyme transport in the plasma in association with transferrin, which can only carry iron in the ferric state.


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