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Cerulenin

A FAS inhibitor
Catalog #: 1579
SKU-Size Size Price Qty
1579-5 5 mg
$125.00
1579-50 50 mg
$775.00
More Sizes Get Quote

Product Details

Alternate Name 2,3-Epoxy-4-oxo-7,10-dodecadienamide
Appearance White to off-white solid
CAS # 17397-89-6
Molecular Formula C₁₂H₁₇NO₃
Molecular Weight 223.3
Purity ≥98%
Solubility DMSO (20 mg/ml) or EtOH (20 mg/ml)
SMILES CC=CCC=CCCC(=O)C1C(O1)C(=O)N
InChi InChI=1S/C12H17NO3/c1-2-3-4-5-6-7-8-9(14)10-11(16-10)12(13)15/h2-3,5-6,10-11H,4,7-8H2,1H3,(H2,13,15)
InChi Key GVEZIHKRYBHEFX-UHFFFAOYSA-N
PubChem CID 272023
MDL Number MFCD00077686
Handling Protect from light and air
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Antibiotic. Fatty acid synthase (FAS) inhibitor, reported to bind in equimolar ratio to β-keto-acyl-ACP synthase, thus inhibiting protein acylation. Produces metabolic effects similar to effects of leptin, but through mechanisms that are independent of, or downstream from, both leptin and melanocortin receptors. Apoptosis inducer. Inhibitor of bacterial fatty acid synthesis (inhibits FabH, FabB and FabF condensation enzymes).


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