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CEP-18770

A potent proteosome inhibitor
Catalog #: 2433
SKU-Size Size Price Qty
2433-5 5 mg
$195.00
2433-25 25 mg
$795.00
More Sizes Get Quote

Product Details

Alternate Name [(1R)-1-[[(2S,3R)-3-Hydroxy-2-[[(6-phenylpyridin-2-yl)carbonyl]amino]-1-oxobutyl]amino]-3-methylbutyl]boronic acid; Delanzomib
Appearance Off-white solid
CAS # 847499-27-8
Molecular Formula C₂₁H₂₈BN₃O₅
Molecular Weight 413.28
Purity ≥98% by HPLC
Solubility DMSO (>70 mg/ml) or EtOH (>70 mg/ml)
SMILES B(C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C1=CC=CC(=N1)C2=CC=CC=C2)(O)O
InChi InChI=1S/C21H28BN3O5/c1-13(2)12-18(22(29)30)24-21(28)19(14(3)26)25-20(27)17-11-7-10-16(23-17)15-8-5-4-6-9-15/h4-11,13-14,18-19,26,29-30H,12H2,1-3H3,(H,24,28)(H,25,27)/t14-,18+,19+/m1/s1
InChi Key SJFBTAPEPRWNKH-CCKFTAQKSA-N
PubChem CID 24800541
Handling Protect from air and mositure
Storage Conditions -20 ̊C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

CEP-18770 is a reversible P2 threonine boronic acid inhibitor of the chymotrypsin-like activity of the proteasome. Displays anti-multimyeloma (MM) effect.


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