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Product Details
| Alternate Name | [(1R)-1-[[(2S,3R)-3-Hydroxy-2-[[(6-phenylpyridin-2-yl)carbonyl]amino]-1-oxobutyl]amino]-3-methylbutyl]boronic acid; Delanzomib |
|---|---|
| Appearance | Off-white solid |
| CAS # | 847499-27-8 |
| Molecular Formula | C₂₁H₂₈BN₃O₅ |
| Molecular Weight | 413.28 |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (>70 mg/ml) or EtOH (>70 mg/ml) |
| SMILES | B(C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C1=CC=CC(=N1)C2=CC=CC=C2)(O)O |
| InChi | InChI=1S/C21H28BN3O5/c1-13(2)12-18(22(29)30)24-21(28)19(14(3)26)25-20(27)17-11-7-10-16(23-17)15-8-5-4-6-9-15/h4-11,13-14,18-19,26,29-30H,12H2,1-3H3,(H,24,28)(H,25,27)/t14-,18+,19+/m1/s1 |
| InChi Key | SJFBTAPEPRWNKH-CCKFTAQKSA-N |
| PubChem CID | 24800541 |
| Handling | Protect from air and mositure |
| Storage Conditions | -20 ̊C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
CEP-18770 is a reversible P2 threonine boronic acid inhibitor of the chymotrypsin-like activity of the proteasome. Displays anti-multimyeloma (MM) effect.
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